Description

2-(Piperazin-1-Ylsulfonyl)Benzonitrile is a high-purity chemical intermediate featuring a benzonitrile core functionalized with a piperazinylsulfonyl group. This compound matters for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly within pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries via parallel synthesis for high-throughput screening (HTS).
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and pesticides.
• Chemical Biology Probe Development: Employed in the design of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, proprietary molecules for clients.

Basic Information

Product Name	2-(Piperazin-1-Ylsulfonyl)Benzonitrile
CAS No.	743440-24-6
Molecular Formula	C11H13N3O2S
Molecular Weight	251.31 g/mol
Synonyms	2-(Piperazin-1-ylsulfonyl)benzonitrile; 2-(1-Piperazinylsulfonyl)benzonitrile; Benzonitrile, 2-(1-piperazinylsulfonyl)-; 2-Piperazin-1-ylsulfonyl-benzonitrile; 743440-24-6; 2-(Piperazine-1-sulfonyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-1-Ylsulfonyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.