Description

5H-Cyclopentapyrazine-2-Carboxamide,6,7-Dihydro-n-(trans-4- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in early-stage drug discovery.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Academic & Institutional Research: Employed in chemical biology and pharmacology research to explore novel biological pathways and mechanisms of action.
• Custom Synthesis Projects: A starting material for the custom manufacturing of specialized compounds for clinical trial material (CTM) production.

Basic Information

Product Name	5H-Cyclopentapyrazine-2-Carboxamide,6,7-Dihydro-n-(trans-4-
CAS No.	742070-33-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	trans-4-(6,7-Dihydro-5H-cyclopenta[d]pyrazine-2-carboxamido)cyclohexanecarboxylic acid; 6,7-Dihydro-5H-cyclopenta[d]pyrazine-2-carboxylic acid, N-[(1r,4r)-4-(carboxy)cyclohexyl]-; 5H-Cyclopentapyrazine-2-carboxamide, 6,7-dihydro-N-(trans-4-aminocyclohexyl)-; CAS 742070-33-3; trans-4-[(6,7-Dihydro-5H-cyclopenta[d]pyrazine-2-carbonyl)amino]cyclohexane-1-carboxylic acid; (1r,4r)-4-({[6,7-Dihydro-5H-cyclopenta[d]pyrazin-2-yl]carbonyl}amino)cyclohexane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5H-Cyclopentapyrazine-2-Carboxamide,6,7-Dihydro-n-(trans-4- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with the stringent requirements of pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.