Description

1-(4-(3-Fluoro-4-Hydroxyphenyl)Piperazin-1-Yl)Ethanone is a high-purity, fluorinated piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and chemical manufacturers in the life sciences sector seeking to develop new therapeutic agents, particularly within central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and psychiatric disorders.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemists exploring structure-activity relationships (SAR) in new molecular entities.
• API Synthesis: Used in the multi-step manufacturing process of potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Employed in biochemical assays and pharmacological studies to investigate specific receptor interactions and pathways.
• Fine Chemical Production: Integral to the production of other specialized fluorinated fine chemicals and advanced intermediates.

Basic Information

Product Name	1-(4-(3-Fluoro-4-Hydroxyphenyl)Piperazin-1-Yl)Ethanone
CAS No.	742067-12-5
Molecular Formula	C12H15FN2O2
Molecular Weight	238.26 g/mol
Synonyms	1-[4-(3-Fluoro-4-hydroxyphenyl)piperazin-1-yl]ethanone; 1-(4-(3-Fluoro-4-hydroxyphenyl)-1-piperazinyl)ethanone; 1-(4-(3-Fluoro-4-hydroxyphenyl)piperazin-1-yl)ethan-1-one; 3-Fluoro-4-(4-acetylpiperazin-1-yl)phenol; 4-(4-Acetyl-1-piperazinyl)-2-fluorophenol; Acetic acid (4-(3-fluoro-4-hydroxyphenyl)-1-piperazinyl) ester; 742067-12-5
EINECS	Contact for details

Quality Control

Our 1-(4-(3-Fluoro-4-Hydroxyphenyl)Piperazin-1-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its chemical nature, keep away from strong alkalis and incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.