Description

(R)-N1-Boc-2-(Benzyloxymethyl)Piperazine is a high-purity, chiral piperazine derivative protected with a tert-butoxycarbonyl (Boc) group. This compound is a critical pharmaceutical intermediate and building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing new drug candidates, including protease inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in the discovery and development of new therapeutic compounds, particularly those targeting enzymes like proteases.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for creating peptide-like molecules with enhanced stability and bioavailability.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined (R)-configuration to impart specific stereochemistry to final molecules.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological pathways and protein function.

Basic Information

Product Name	(R)-N1-Boc-2-(Benzyloxymethyl)Piperazine
CAS No.	740806-54-6
Molecular Formula	C18H28N2O3
Molecular Weight	320.43 g/mol
Synonyms	1-Boc-2-(Benzyloxymethyl)-(R)-Piperazine; tert-Butyl (R)-2-(benzyloxymethyl)piperazine-1-carboxylate; (R)-1-Boc-2-(Benzyloxymethyl)Piperazine; (R)-N-Boc-2-(Benzyloxymethyl)Piperazine; (2R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-2-(phenylmethoxymethyl)piperazine; (R)-1-(tert-Butoxycarbonyl)-2-(benzyloxymethyl)piperazine; Boc-(R)-2-(Benzyloxymethyl)piperazine
EINECS	Contact for details

Quality Control

Our (R)-N1-Boc-2-(Benzyloxymethyl)Piperazine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. Our quality commitment aligns with standards expected for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.