Description

2-Piperazinecarbonitrile, 1-(Chloroacetyl)- (9Ci) is a versatile and high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a key building block in the development of complex, nitrogen-containing heterocycles, particularly in the pharmaceutical sector. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and fine chemicals.

Application

• As a critical pharmaceutical intermediate in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Used in the research and development of agrochemicals, such as herbicides and fungicides, requiring specific piperazine-based structures.
• Serves as a key precursor for the preparation of complex ligands and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Employed in the synthesis of specialty polymers and advanced materials where its functional groups enable specific cross-linking or property modifications.
• Utilized in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal chemistry.

Basic Information

Product Name	2-Piperazinecarbonitrile, 1-(Chloroacetyl)- (9Ci)
CAS No.	739364-92-2
Molecular Formula	C7H10ClN3O
Molecular Weight	187.63 g/mol
Synonyms	1-(Chloroacetyl)piperazine-2-carbonitrile; 1-(2-Chloroacetyl)piperazine-2-carbonitrile; 2-Cyano-1-(chloroacetyl)piperazine; 1-Chloroacetyl-2-cyanopiperazine; 2-Piperazinecarbonitrile, 1-(chloroacetyl)-; N-(Chloroacetyl)-2-cyanopiperazine; (Chloroacetyl)piperazine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Piperazinecarbonitrile, 1-(Chloroacetyl)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.