Description

(4-Amino-Piperidin-1-Yl)-(4-Fluoro-Phenyl)-Methanone is a high-purity pharmaceutical intermediate featuring a piperidine scaffold with both amino and fluorophenyl ketone functional groups. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel compounds.
• CNS Drug Development: Serves as a building block for molecules targeting neurological receptors and enzymes.
• Oncology Research: Employed in the development of kinase inhibitors and other targeted cancer therapies.
• Chemical Library Synthesis: Used for the generation of diverse compound libraries for high-throughput screening.
• Process Chemistry: Scaled-up for route development and optimization in pilot and commercial API manufacturing.

Basic Information

Product Name	(4-Amino-Piperidin-1-Yl)-(4-Fluoro-Phenyl)-Methanone
CAS No.	739339-41-4
Molecular Formula	C12H15FN2O
Molecular Weight	222.26 g/mol
Synonyms	1-(4-Fluorobenzoyl)-4-aminopiperidine; 4-Amino-1-(4-fluorobenzoyl)piperidine; (4-Aminopiperidin-1-yl)(4-fluorophenyl)methanone; 4-Fluoro-N-(4-aminopiperidin-1-yl)benzamide; 739339-41-4; 4-Amino-1-(4-fluorobenzoyl)piperidine; 1-(4-Fluorobenzoyl)piperidin-4-amine
EINECS	Contact for details

Quality Control

Our (4-Amino-Piperidin-1-Yl)-(4-Fluoro-Phenyl)-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring material for GLP and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.