Description

3-Fluoropiperidine Hydrochloride is a versatile fluorinated piperidine derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in the strategic introduction of a fluorine atom into the piperidine scaffold, which can significantly alter the physicochemical and biological properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances bioactivity and environmental stability.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes and enzyme inhibitors to study biological pathways.
• Material Science Research: Acts as a precursor for specialty polymers and advanced materials requiring fluorinated amine components.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create novel ligands and catalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Fluoropiperidine Hydrochloride
CAS No.	737000-77-0
Molecular Formula	C5H11ClFN
Molecular Weight	139.60 g/mol
Synonyms	3-Fluoropiperidine HCl; 3-Fluoro-piperidine hydrochloride; Piperidine, 3-fluoro-, hydrochloride; 3-Fluoropiperidinium chloride; 3-Fluoropiperidine monohydrochloride; 3-Fluoro-1-azacyclohexane hydrochloride; 3-Fluoropiperidine, hydrochloride; 3-Fluoropiperidine HCl salt
EINECS	Contact for details

Quality Control

Our 3-Fluoropiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.