Description

1-(2-Chloro-4-Fluorophenyl)Piperazine is a high-purity, functionalized piperazine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific halogenated aromatic structure enables precise molecular modifications. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and psychiatric therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its halogenated phenylpiperazine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Biochemical Research: Employed in life science research as a tool compound for studying receptor interactions and signal transduction pathways.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of polymers with specific thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the fine chemical and pharmaceutical markets.

Basic Information

Product Name	1-(2-Chloro-4-Fluorophenyl)Piperazine
CAS No.	736122-94-4
Molecular Formula	C10H12ClFN2
Molecular Weight	214.67 g/mol
Synonyms	2-Chloro-4-fluorophenylpiperazine; 1-(2-Chloro-4-fluorophenyl)piperazine; N-(2-Chloro-4-fluorophenyl)piperazine; 2-Chloro-4-fluoro-1-piperazin-1-ylbenzene; 2-Chloro-4-fluorophenyl-piperazine; 1-(2-Chloro-4-fluoro-phenyl)-piperazine
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-4-Fluorophenyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.