Description

1-(3-Azetidinyl)-4-[4-(Trifluoromethyl)Phenyl]-Piperazine CAS NO 732233-27-1 is a specialized heterocyclic organic compound featuring a piperazine core substituted with an azetidine ring and a trifluoromethylphenyl group. This molecular architecture makes it a valuable high-purity building block for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Serves as a building block for creating novel ligands targeting G-protein-coupled receptors (GPCRs) and other biological targets.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for potential active pharmaceutical ingredients (APIs).
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.
• Material Science: Investigated as a monomer or additive for specialty polymers with unique thermal or chemical properties.

Basic Information

Product Name	1-(3-Azetidinyl)-4-[4-(Trifluoromethyl)Phenyl]-Piperazine
CAS No.	732233-27-1
Molecular Formula	C14H18F3N3
Molecular Weight	285.31 g/mol
Synonyms	1-(Azetidin-3-yl)-4-[4-(trifluoromethyl)phenyl]piperazine; 4-[4-(Trifluoromethyl)phenyl]-1-(3-azetidinyl)piperazine; 1-(3-Azetidinyl)-4-(4-trifluoromethylphenyl)piperazine; 1-(Azetidin-3-yl)-4-(4-(trifluoromethyl)phenyl)piperazine; 732233-27-1; 4-(4-Trifluoromethylphenyl)-1-(3-azetidinyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(3-Azetidinyl)-4-[4-(Trifluoromethyl)Phenyl]-Piperazine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.