Description

(4-Phenyl-Piperazin-1-Yl)-Piperidin-4-Yl-Methanone Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, especially within the central nervous system (CNS) and receptor-targeted drug discovery sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and optimizing new drug candidates in high-throughput screening.
• CNS Drug Development: Particularly relevant for research targeting neurological receptors and pathways due to its piperazine-piperidine pharmacophore.
• Chemical Biology: Employed in the study of protein-ligand interactions and biochemical pathway modulation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	(4-Phenyl-Piperazin-1-Yl)-Piperidin-4-Yl-Methanone Hydrochloride
CAS No.	731832-24-9
Molecular Formula	C16H23N3O · HCl
Molecular Weight	309.84 g/mol (Free base: 273.38 g/mol)
Synonyms	1-(4-Piperidinyl)-2-(4-phenyl-1-piperazinyl)ethanone hydrochloride; 4-[(4-Phenylpiperazin-1-yl)carbonyl]piperidine hydrochloride; 1-(4-Phenylpiperazin-1-yl)-2-piperidin-4-ylethanone hydrochloride; 4-Phenyl-1-(4-piperidinylcarbonyl)piperazine hydrochloride; (4-Phenylpiperazino)(4-piperidinyl)methanone hydrochloride; 4-(4-Phenylpiperazine-1-carbonyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (4-Phenyl-Piperazin-1-Yl)-Piperidin-4-Yl-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.