Description

4-Methoxycarbonylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-purity piperazine derivative, serving as a critical protected intermediate in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of functionalized piperazine scaffolds, which are essential pharmacophores in modern drug discovery. This compound is particularly vital for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents, antivirals, and anti-cancer compounds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require a functionalized piperazine core.
• Peptidomimetics & PROTACs: Serves as a crucial linker or spacer component in the design of peptide mimics and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes and labeled compounds for biochemical and pharmacological research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services and contract research organizations (CROs/CMOs) developing proprietary compounds for clients.

Basic Information

Item	Details
Product Name	4-Methoxycarbonylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	731810-20-1
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	1-Boc-4-(methoxycarbonylmethyl)piperazine; tert-Butyl 4-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(methoxycarbonylmethyl)piperazine; 4-(Methoxycarbonylmethyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; Piperazine-1-carboxylic acid, 4-(methoxycarbonylmethyl)-, 1,1-dimethylethyl ester; Boc-4-(CH2CO2Me)-piperazine
EINECS	Contact for details

Quality Control

Our 4-Methoxycarbonylmethyl-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.