Description

2-Chloro-1-[4-(Furan-2-Carbonyl)-Piperazin-1-Yl]-Ethanone is a high-purity synthetic intermediate featuring a reactive chloroacetyl group linked to a furan-carbonyl piperazine scaffold. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly within pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or requiring a piperazine pharmacophore.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides where the furan and piperazine moieties can contribute to biological activity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function or protein-protein interactions.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Chloro-1-[4-(Furan-2-Carbonyl)-Piperazin-1-Yl]-Ethanone
CAS No.	729578-87-4
Molecular Formula	C11H11ClN2O3
Molecular Weight	254.67 g/mol
Synonyms	2-Chloro-1-(4-(furan-2-carbonyl)piperazin-1-yl)ethanone; 1-(4-(2-Furoyl)-1-piperazinyl)-2-chloroethanone; 2-Chloro-1-[4-(2-furoyl)piperazin-1-yl]ethan-1-one; 2-Chloro-1-(4-(2-furoyl)piperazin-1-yl)ethanone; Ethanone, 2-chloro-1-[4-(2-furanylcarbonyl)-1-piperazinyl]-; 729578-87-4; Furan-2-carbonyl piperazine chloroethanone derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-[4-(Furan-2-Carbonyl)-Piperazin-1-Yl]-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.