Description

5-Piperazin-1-Ylmethyl-6-p-Tolyl-Imidazo[2,1-B]Thiazole is a high-purity, advanced pharmaceutical intermediate belonging to the imidazothiazole class of heterocyclic compounds. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. Pharmaceutical R&D teams and fine chemical manufacturers need this material for developing next-generation therapeutic agents, leveraging its unique molecular scaffold to create compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Development: Serves as a core structural component for the development of new Active Pharmaceutical Ingredients targeting specific receptors.
• Biochemical Research: Used as a reference standard or a probe molecule in pharmacological and biochemical screening assays.
• Organic Synthesis Building Block: Employed in complex organic synthesis for constructing fused heterocyclic systems with potential bioactivity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of pharmaceutical compounds.
• Academic Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) and novel synthetic methodologies.

Basic Information

Item	Details
Product Name	5-Piperazin-1-Ylmethyl-6-p-Tolyl-Imidazo[2,1-B]Thiazole
CAS No.	727975-67-9
Molecular Formula	C18H22N4S
Molecular Weight	326.46 g/mol
Synonyms	5-[(Piperazin-1-yl)methyl]-6-(4-methylphenyl)imidazo[2,1-b][1,3]thiazole; 6-p-Tolyl-5-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazole; 5-(Piperazin-1-ylmethyl)-6-(p-tolyl)imidazo[2,1-b]thiazole; Imidazo[2,1-b]thiazole, 5-(1-piperazinylmethyl)-6-(4-methylphenyl)-; 727975-67-9; 5-Piperazin-1-ylmethyl-6-p-tolylimidazo[2,1-b]thiazole
EINECS	Contact for details

Quality Control

Our 5-Piperazin-1-Ylmethyl-6-p-Tolyl-Imidazo[2,1-B]Thiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.