Description

(3R,4R)-4-(Boc-Amino)-3-Hydroxypiperidine CAS NO 724788-29-8 is a high-purity, stereochemically defined piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a protected amino and a hydroxyl group in a specific three-dimensional orientation, enabling the efficient construction of complex molecular architectures with high enantiomeric purity. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs), chiral catalysts, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule therapeutics.
• Agrochemical Research: Used in constructing chiral scaffolds for novel herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in stereoselective transformations.
• Peptidomimetics & Conformational Studies: Integral for designing and synthesizing peptide analogs and studying bioactive conformations.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic and medicinal chemistry research.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for client-specific molecule development.

Basic Information

Product Name	(3R,4R)-4-(Boc-Amino)-3-Hydroxypiperidine
CAS No.	724788-29-8
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	1-Boc-3,4-piperidinediol, (3R,4R)- isomer; (3R,4R)-4-[(tert-Butoxycarbonyl)amino]-3-hydroxypiperidine; (3R,4R)-1-Boc-4-amino-3-hydroxypiperidine; tert-Butyl (3R,4R)-3-hydroxy-4-piperidinylcarbamate; (3R,4R)-4-(Boc-amino)piperidin-3-ol; Boc-4-amino-3-hydroxy-(3R,4R)-piperidine; (3R,4R)-3-Hydroxy-4-(Boc-amino)piperidine
EINECS	Contact for details

Quality Control

Our (3R,4R)-4-(Boc-Amino)-3-Hydroxypiperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.