Description

1-Azabicyclo[4.2.0]Oct-2-En-8-One,(6R)-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and bicyclic lactam structure. This compound is of significant value in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel β-lactam antibiotics and other therapeutic agents. It is primarily sought by research institutions, custom synthesis organizations, and pharmaceutical manufacturers engaged in the development of next-generation antibacterial and anti-inflammatory drugs.

Application

• Key Intermediate in β-Lactam Antibiotic Synthesis: Serves as a crucial chiral building block for the research and production of novel carbapenem and penem class antibiotics.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for the design and synthesis of new chemical entities (NCEs) targeting bacterial infections.
• Custom Synthesis and Process Chemistry: Employed by contract research and manufacturing organizations (CROs/CMOs) for the scalable production of proprietary drug candidates.
• Academic Research: Utilized in university and institutional labs for studying enzyme inhibition, mechanism of action, and structure-activity relationships (SAR).
• Precursor for Biologically Active Molecules: Acts as a starting material for synthesizing more complex molecules with potential anti-inflammatory or neurological activity.

Basic Information

Product Name	1-Azabicyclo[4.2.0]Oct-2-En-8-One,(6R)-(9Ci)
CAS No.	724705-43-5
Molecular Formula	C7H9NO
Molecular Weight	123.15 g/mol
Synonyms	(6R)-1-Azabicyclo[4.2.0]oct-2-en-8-one; (6R)-1-Aza-bicyclo[4.2.0]oct-2-en-8-one; (6R)-ABCO-2-en-8-one; (6R)-Bicyclic β-lactam intermediate; (6R)-Octahydro-1H-azocin-2-one derivative; 724705-43-5; (6R)-enantiomer of 1-Azabicyclo[4.2.0]oct-2-en-8-one
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[4.2.0]Oct-2-En-8-One,(6R)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for pharmaceutical R&D. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles. Our quality system is designed to support regulatory filings, and we can supply material compliant with current Good Manufacturing Practice (cGMP) standards for advanced clinical-stage projects upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (6R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.