Description

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine is a high-value, nitrogen-rich heterocyclic compound featuring a trifluoromethyl group, a key structural motif prized in modern chemical synthesis. This molecule matters as a sophisticated pharmaceutical intermediate and agrochemical building block, where its unique scaffold contributes to enhanced biological activity, metabolic stability, and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the triazolopyrazine core.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds and probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a precursor for advanced functional materials, including ligands for catalysis and components in organic electronics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up services.

Basic Information

Product Name	3-(Trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine
CAS No.	723286-87-1
Molecular Formula	C7H9F3N4
Molecular Weight	206.17 g/mol
Synonyms	5-Methyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine; 5-Methyl-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine; 3-(Trifluoromethyl)-5-methyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine; [1,2,4]Triazolo[4,3-a]pyrazine, 3-(trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-; 723286-87-1; 5-Methyl-3-trifluoromethyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
EINECS	Contact for details

Quality Control

Our production of 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-5-methyl-[1,2,4]triazolo[4,3-a]pyrazine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.