Description

n-tert-Butyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate belonging to the fused triazolopyrazine class of heterocyclic compounds. Its molecular architecture makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. This compound is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery and process development programs requiring structurally complex and precisely functionalized intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization within the triazolopyrazine chemical space.
• Active Pharmaceutical Ingredient (API) Development: Employed in the scalable process chemistry for developing new APIs targeting specific receptor sites.
• Biochemical Research: Utilized as a reference standard or probe molecule in pharmacological assays and enzyme inhibition studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	n-tert-Butyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine-3-Carboxamide
CAS No.	723286-71-3
Molecular Formula	C₁₁H₁₉N₅O
Molecular Weight	237.30 g/mol
Synonyms	1-(1,1-Dimethylethyl)-4,5,6,7-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine-3-carboxamide; 1-tert-Butyl-4,5,6,7-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine-3-carboxamide; 1-(tert-Butyl)-4,5,6,7-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine-3-carboxamide; 723286-71-3; Triazolopyrazine-3-carboxamide derivative; BTTCP; tert-Butyl tetrahydrotriazolopyrazine carboxamide
EINECS	Contact for details

Quality Control

Our n-tert-Butyl-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine-3-Carboxamide is manufactured under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with every batch. Our quality commitment ensures reliable consistency and traceability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.