Description

5-Trimethylphenyl)Piperazine is a high-purity, specialized aromatic piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D, agrochemical, and specialty chemical manufacturers seeking to develop new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of central nervous system (CNS) active compounds, receptor ligands, and other novel therapeutic agents.
• Agrochemical Research: Building block for developing new crop protection agents, including fungicides and insecticides.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate for dyes, pigments, and other performance chemicals requiring a substituted piperazine moiety.
• Academic & Industrial R&D: Serves as a valuable reagent for methodological development and structure-activity relationship (SAR) studies in medicinal chemistry.

Basic Information

Product Name	5-Trimethylphenyl)Piperazine
CAS No.	722491-58-9
Molecular Formula	C13H20N2
Molecular Weight	204.31 g/mol
Synonyms	1-(3,4,5-Trimethylphenyl)piperazine; 3,4,5-Trimethylphenylpiperazine; Piperazine, 1-(3,4,5-trimethylphenyl)-; 5-Trimethylphenyl-piperazine; (3,4,5-Trimethylphenyl)piperazine
EINECS	Contact for details

Quality Control

Our 5-Trimethylphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.