Description

[4-(2-Cyano-Ethyl)-Piperazin-1-Yl]-Acetic Acid is a versatile piperazine derivative building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a cyanoethyl and an acetic acid functional group on the piperazine core, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Chelator Precursor: Serves as a starting material for creating specialized ligands used in catalysis and metal ion sequestration.
• Polymer Modification: Employed to introduce functional piperazine groups into polymer chains, altering physical and chemical properties.
• Bioconjugation Chemistry: The reactive acid and amine groups facilitate its use in linking molecules, such as in antibody-drug conjugate (ADC) research.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry optimization in academic and industrial labs.

Basic Information

Item	Detail
Product Name	[4-(2-Cyano-Ethyl)-Piperazin-1-Yl]-Acetic Acid
CAS No.	722491-37-4
Molecular Formula	C9H15N3O2
Molecular Weight	197.24 g/mol
Synonyms	2-[4-(2-Cyanoethyl)piperazin-1-yl]acetic acid; 1-Carboxymethyl-4-(2-cyanoethyl)piperazine; 4-(2-Cyanoethyl)piperazine-1-acetic acid; (4-(2-Cyanoethyl)piperazin-1-yl)acetic acid; N-(2-Cyanoethyl)-N-(carboxymethyl)piperazine; Piperazine-1-acetic acid, 4-(2-cyanoethyl)- derivative
EINECS	Contact for details

Quality Control

Our [4-(2-Cyano-Ethyl)-Piperazin-1-Yl]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.