Description

Benzyl 4-Cyanopiperazine-1-Carboxylate is a high-purity, versatile piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional nature, featuring both a protected amine and a reactive nitrile group, enabling its use in constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging the piperazine scaffold for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Peptidomimetics: Employed in the design and synthesis of peptide analogs and mimetics due to its constrained cyclic amine structure.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Benzyl 4-Cyanopiperazine-1-Carboxylate
CAS No.	721450-32-4
Molecular Formula	C13H15N3O2
Molecular Weight	245.28 g/mol
Synonyms	1-CBz-4-Cyanopiperazine; Benzyl 4-Cyano-1-piperazinecarboxylate; 4-Cyano-1-(phenylmethoxycarbonyl)piperazine; 1-[(Benzyloxy)carbonyl]-4-cyanopiperazine; 4-Cyanopiperazine-1-carboxylic acid benzyl ester; Piperazine-1-carboxylic acid benzyl ester, 4-cyano-; Bn 4-CN-piperazine-1-CO2; 1-CBz-4-CNPz
EINECS	Contact for details

Quality Control

Our Benzyl 4-Cyanopiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) for all shipments. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.