Description

Piperazine, 1-[(2S)-2-Amino-4-Methyl-1-Oxopentyl]-4-Ethyl- (9Ci) is a specialized chiral piperazine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex, biologically active molecules, particularly in the pharmaceutical sector. It is primarily needed by research institutions and manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry is critical. The compound is supplied with a CAS number of 720656-32-6.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific stereochemical requirements for enhanced efficacy.
• Peptidomimetics Research: Serves as a constrained scaffold in the design of peptide analogs to improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring high-purity, stereochemically defined intermediates.

Basic Information

Item	Detail
Product Name	Piperazine, 1-[(2S)-2-Amino-4-Methyl-1-Oxopentyl]-4-Ethyl- (9Ci)
CAS No.	720656-32-6
Molecular Formula	C12H25N3O
Molecular Weight	227.35 g/mol
Synonyms	1-[(2S)-2-Amino-4-methyl-1-oxopentyl]-4-ethylpiperazine; (2S)-2-Amino-4-methyl-N-(4-ethylpiperazin-1-yl)pentanamide; 4-Ethyl-1-[(2S)-2-amino-4-methylpentanoyl]piperazine; L-Leucinamide, N-(4-ethyl-1-piperazinyl)-; A chiral leucine-piperazine derivative
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[(2S)-2-Amino-4-Methyl-1-Oxopentyl]-4-Ethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.