Description

3-Oxo-3-[4-(2-Phenylethyl)Piperazin-1-Yl]Propanenitrile is a high-value, specialized chemical intermediate featuring a piperazine core linked to a nitrile and ketone functional group. This unique structure makes it a critical building block for the synthesis of complex pharmacologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for creating novel compounds, particularly in central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological and psychiatric disorders.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex organic molecules requiring a functionalized piperazine moiety.
• Biochemical Research: Employed as a tool compound or ligand precursor in biochemical assays and receptor binding studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	3-Oxo-3-[4-(2-Phenylethyl)Piperazin-1-Yl]Propanenitrile
CAS No.	717858-21-4
Molecular Formula	C15H19N3O
Molecular Weight	257.33 g/mol
Synonyms	3-[4-(2-Phenylethyl)piperazin-1-yl]-3-oxopropanenitrile; 3-Oxo-3-(4-phenethylpiperazin-1-yl)propanenitrile; 1-Phenethylpiperazine-1-carboxamide, N-cyanoacetyl-; 3-Oxo-3-(4-phenethyl-1-piperazinyl)propanenitrile; Propanenitrile, 3-oxo-3-[4-(2-phenylethyl)-1-piperazinyl]-; 717858-21-4
EINECS	Contact for details

Quality Control

Our 3-Oxo-3-[4-(2-Phenylethyl)Piperazin-1-Yl]Propanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.