Description

(+/-)-4-[4-(Dimethylamino)-1-(4-Fluorophenyl)-1-Hydroxybutyl]-3-(Hydroxymethyl)-Benzonitrile, Oxalate is a high-purity, complex organic compound primarily utilized as a key intermediate in advanced pharmaceutical synthesis. This compound is critical for research and development in medicinal chemistry, particularly in the creation of novel therapeutic agents targeting the central nervous system. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) for neurological and psychiatric drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Biochemical Research: Investigated for its interaction with specific biological targets and receptors in preclinical studies.

Basic Information

Product Name	(+/-)-4-[4-(Dimethylamino)-1-(4-Fluorophenyl)-1-Hydroxybutyl]-3-(Hydroxymethyl)-Benzonitrile, Oxalate
CAS No.	717133-32-9
Molecular Formula	C22H25FN2O2 • C2H2O4
Molecular Weight	460.47 g/mol
Synonyms	4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile oxalate; Escitalopram Oxalate Intermediate; Citalopram Related Compound; (±)-4-[4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)benzonitrile oxalic acid salt; 1-(4-Fluorophenyl)-1-[4-(dimethylamino)-1-(3-hydroxymethylphenyl)butyl] oxalate; Sertraline analogue intermediate; Benzonitrile derivative oxalate salt
EINECS	Contact for details

Quality Control

Our (+/-)-4-[4-(Dimethylamino)-1-(4-Fluorophenyl)-1-Hydroxybutyl]-3-(Hydroxymethyl)-Benzonitrile, Oxalate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.