Description

3-Piperidinecarboxylic Acid, 4-Hydroxy-1-Methyl-, (3R,4S)- (9Ci) is a high-purity chiral piperidine derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical agents, particularly in the creation of complex molecules with specific stereochemical requirements. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of active pharmaceutical ingredients (APIs), drug discovery, and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Active Pharmaceutical Ingredient (API) Development: Used in research and development for constructing the core scaffold of potential new therapeutic agents.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective chemical reactions to induce desired optical activity in final products.
• Chemical Research: Serves as a valuable reference standard and starting material in academic and industrial research for exploring new chemical entities.
• Process Chemistry Optimization: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	3-Piperidinecarboxylic Acid, 4-Hydroxy-1-Methyl-, (3R,4S)- (9Ci)
CAS No.	716362-70-8
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	(3R,4S)-4-Hydroxy-1-methylpiperidine-3-carboxylic acid; (3R,4S)-1-Methyl-4-hydroxypiperidine-3-carboxylic acid; 4-Hydroxy-1-methylpiperidine-3-carboxylic acid (3R,4S)-isomer; 3-Carboxy-1-methyl-4-hydroxypiperidine, (3R,4S)-; 716362-70-8; (3R,4S)-rel-4-Hydroxy-1-methyl-3-piperidinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-Piperidinecarboxylic Acid, 4-Hydroxy-1-Methyl-, (3R,4S)- (9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.