Description

2(1H)-Quinoxalinone,3,4-Dihydro-3-(Hydroxymethyl)-,(3R)-(9Ci) is a high-purity, chiral quinoxalinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and chiral building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by pharmaceutical R&D teams and contract research organizations (CROs) engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries via parallel synthesis to explore structure-activity relationships (SAR).
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in stereoselective synthesis to introduce the (3R)-configuration into complex molecules.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Fine Chemical Production: Integrated into multi-step synthesis processes for producing specialty chemicals with high added value.
• Academic Research: Utilized in university and institutional labs for studies in heterocyclic chemistry and chiral molecule synthesis.

Basic Information

Product Name	2(1H)-Quinoxalinone,3,4-Dihydro-3-(Hydroxymethyl)-,(3R)-(9Ci)
CAS No.	714569-16-1
Molecular Formula	C9H10N2O2
Molecular Weight	178.19 g/mol
Synonyms	(3R)-3,4-Dihydro-3-(hydroxymethyl)-2(1H)-quinoxalinone; (R)-3,4-Dihydro-3-(hydroxymethyl)-2(1H)-quinoxalinone; (R)-3-(Hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one; 3,4-Dihydro-3-(hydroxymethyl)-2(1H)-quinoxalinone, (R)-; (R)-3,4-Dihydro-3-(hydroxymethyl)-1H-quinoxalin-2-one; 714569-16-1; (R)-3-Hydroxymethyl-3,4-dihydro-1H-quinoxalin-2-one; Quinoxalinone derivative, (R)-isomer
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinoxalinone,3,4-Dihydro-3-(Hydroxymethyl)-,(3R)-(9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) documenting purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.