Description

1(2H)-Pyrazinecarboxylicacid,3-Amino-5,6-Dihydro-,1,1-Dimethylethylester CAS NO 714192-90-2 is a high-purity, protected amino acid derivative belonging to the pyrazine class, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling the controlled introduction of functionalized pyrazine moieties into complex molecular architectures, which is essential for developing novel compounds with targeted properties. This intermediate is particularly vital for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize potential active ingredients and fine-tune molecular characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Peptidomimetics & Bioactive Molecule Design: Serves as a constrained, heterocyclic amino acid analog for constructing peptide-like molecules with enhanced metabolic stability and receptor selectivity.
• Ligand & Catalyst Development: Employed in the synthesis of specialized chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	1(2H)-Pyrazinecarboxylicacid,3-Amino-5,6-Dihydro-,1,1-Dimethylethylester
CAS No.	714192-90-2
Molecular Formula	C11H17N3O2
Molecular Weight	223.27 g/mol
Synonyms	tert-Butyl 3-amino-5,6-dihydro-1(2H)-pyrazinecarboxylate; 3-Amino-5,6-dihydro-2H-pyrazine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-amino-3,4-dihydro-2H-pyrazine-1-carboxylate; 3-Amino-1-Boc-1,2,3,6-tetrahydropyrazine; 1-Boc-3-amino-1,2,3,6-tetrahydropyrazine; 3-Amino-1,2,3,6-tetrahydropyrazine-1-carboxylic acid tert-butyl ester; Boc-3-amino-DHP; 3-Amino-DHP-Boc
EINECS	Contact for details

Quality Control

Every batch of 1(2H)-Pyrazinecarboxylicacid,3-Amino-5,6-Dihydro-,1,1-Dimethylethylester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (IR, NMR), and impurity profiles is provided with each shipment. We support development projects with custom purity grades and can align with cGMP standards for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.