Description

Piperazine, 1-(Chloroacetyl)-4-(2-Methylpropyl)- (9Ci) is a specialized piperazine derivative featuring a chloroacetyl group and an isobutyl substituent. This molecular architecture makes it a valuable high-purity intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by pharmaceutical R&D and custom synthesis organizations seeking to develop novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its piperazine core for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Custom Fine Chemical Production: Employed in contract manufacturing for producing high-value, low-volume specialty chemicals.
• Bioconjugation and Linker Chemistry: The reactive chloroacetyl group enables its use in creating protein-drug conjugates or chemical linkers.
• Academic and Industrial Research: A critical reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Piperazine, 1-(Chloroacetyl)-4-(2-Methylpropyl)- (9Ci)
CAS No.	713522-75-9
Molecular Formula	C10H19ClN2O
Molecular Weight	218.73 g/mol
Synonyms	1-(Chloroacetyl)-4-isobutylpiperazine; 4-Isobutyl-1-(chloroacetyl)piperazine; N-Chloroacetyl-N'-isobutylpiperazine; 1-Chloroacetyl-4-(2-methylpropyl)piperazine; Piperazine, 1-(chloroacetyl)-4-(2-methylpropyl)-; Isobutylpiperazine chloroacetamide
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(Chloroacetyl)-4-(2-Methylpropyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.