Description

(4-Isobutyl-Piperazin-1-Yl)-Oxo-Acetic Acid is a high-purity synthetic intermediate of significant importance in modern pharmaceutical research and development. Its value lies in its role as a key building block for constructing complex molecules, particularly those targeting neurological and cardiovascular pathways. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for API synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry & Scale-Up: Serves as a key starting material or intermediate in the development and optimization of scalable synthetic routes for drug manufacturing.
• Bioconjugation & Probe Development: Potential utility in creating chemical probes or bioconjugates for biochemical and diagnostic research due to its reactive functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds and custom APIs.

Basic Information

Product Name	(4-Isobutyl-Piperazin-1-Yl)-Oxo-Acetic Acid
CAS No.	713522-59-9
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	2-Oxo-2-[(4-isobutylpiperazin-1-yl)]acetic acid; Glyoxylic acid, (4-isobutyl-1-piperazinyl)-; 1-(Carboxymethyl)-4-isobutylpiperazine-2,3-dione (tautomeric form); 4-Isobutylpiperazine-1-glyoxylic acid; (4-Isobutyl-1-piperazinyl)oxoacetic acid; 2-(4-Isobutylpiperazin-1-yl)-2-oxoacetic acid
EINECS	Contact for details

Quality Control

Our (4-Isobutyl-Piperazin-1-Yl)-Oxo-Acetic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material manufactured under GMP (Good Manufacturing Practice) guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.