Description

n-(5-Bromo-Pyrazin-2-Yl)-2,2-Dimethyl-Propionamide is a high-purity brominated pyrazine derivative, a crucial building block in modern organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides, herbicides, and fungicides where the bromopyrazine moiety imparts specific biological activity.
• Material Science Research: Serves as a precursor for the synthesis of functionalized heterocyclic compounds used in organic electronic materials and ligands for catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	n-(5-Bromo-Pyrazin-2-Yl)-2,2-Dimethyl-Propionamide
CAS No.	710322-28-4
Molecular Formula	C9H12BrN3O
Molecular Weight	258.12 g/mol
Synonyms	5-Bromo-N-(2,2-dimethylpropanoyl)pyrazin-2-amine; 2,2-Dimethyl-N-(5-bromopyrazin-2-yl)propanamide; 5-Bromo-2-pivalamidopyrazine; Pivalamide, N-(5-bromo-2-pyrazinyl)-; 710322-28-4; 5-Bromo-2-pivalamidopyrazine; N-(5-Bromopyrazin-2-yl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-Pyrazin-2-Yl)-2,2-Dimethyl-Propionamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and process chemistry. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Specifications can be tailored to meet specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.