Description

Piperazine, 1-[[3-Methyl-4-(1-Methylethyl)-5-Oxo-2(5H)-Isoxazolyl]Carbonyl]-4-(Phenylmethyl)- (9Ci) is a specialized heterocyclic organic compound that serves as a crucial advanced pharmaceutical intermediate (API intermediate) in modern synthetic chemistry. Its complex molecular architecture, featuring fused piperazine and isoxazolone rings, makes it a valuable building block for constructing molecules with targeted biological activity. This high-purity intermediate is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or anti-infective targets.
• Medicinal Chemistry Research: Used as a scaffold or building block in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Organic Synthesis: Serves as a versatile reagent for constructing complex nitrogen-containing heterocycles in academic and industrial laboratories.
• Bioconjugation & Probe Development: Potential use in creating chemical probes or conjugates for biochemical and pharmacological research due to its reactive carbonyl and aromatic groups.

Basic Information

Product Name	Piperazine, 1-[[3-Methyl-4-(1-Methylethyl)-5-Oxo-2(5H)-Isoxazolyl]Carbonyl]-4-(Phenylmethyl)- (9Ci)
CAS No.	706804-17-3
Molecular Formula	C20H25N3O3
Molecular Weight	355.43 g/mol
Synonyms	1-[(3-Methyl-4-isopropyl-5-oxo-4,5-dihydroisoxazol-2-yl)carbonyl]-4-benzylpiperazine; 4-Benzyl-1-[(3-methyl-4-propan-2-yl-5-oxo-1,2-oxazol-2-yl)carbonyl]piperazine; 1-[[3-Methyl-4-(1-Methylethyl)-5-Oxo-2(5H)-Isoxazolyl]Carbonyl]-4-(Phenylmethyl)piperazine; 4-Benzyl-1-({3-methyl-4-[(1-methylethyl)-5-oxo-2,5-dihydroisoxazol-2-yl]}carbonyl)piperazine; Piperazine derivative (CAS 706804-17-3); Advanced Piperazine-Isoxazolone Intermediate.
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support development and cGMP manufacturing needs with reliable, traceable, and well-characterized material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.