Description

Piperazine, 1-Methyl-4-[[3-Methyl-4-(1-Methylethyl)-5-Oxo-2(5H)-Isoxazolyl]Carbonyl]- (9Ci) is a specialized heterocyclic organic compound that serves as a critical synthetic intermediate in advanced pharmaceutical research and development. Its unique molecular architecture, featuring a piperazine ring fused with an isoxazolone moiety, makes it a valuable building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new bioactive compounds.
• Agrochemical Synthesis: Intermediate in the development of new generation pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	Piperazine, 1-Methyl-4-[[3-Methyl-4-(1-Methylethyl)-5-Oxo-2(5H)-Isoxazolyl]Carbonyl]- (9Ci)
CAS No.	706804-15-1
Molecular Formula	C14H21N3O3
Molecular Weight	279.34 g/mol
Synonyms	1-Methyl-4-[(3-methyl-4-propan-2-yl-5-oxo-2H-isoxazol-2-yl)carbonyl]piperazine; 1-Methyl-4-[(3-methyl-4-isopropyl-5-oxo-4,5-dihydroisoxazol-2-yl)carbonyl]piperazine; 1-Methyl-4-({3-methyl-4-[(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]}carbonyl)piperazine; Piperazine derivative CAS 706804-15-1; 4-[(3-Methyl-4-isopropyl-5-oxo-2-isoxazolin-2-yl)carbonyl]-1-methylpiperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-Methyl-4-[[3-Methyl-4-(1-Methylethyl)-5-Oxo-2(5H)-Isoxazolyl]Carbonyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical-grade intermediates. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) and spectroscopic confirmation are provided for every shipment. Our quality commitment aligns with cGMP principles where applicable for non-GMP material, ensuring reliable supply for your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.