Description

Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl- is a high-purity, synthetically derived chiral amino acid derivative featuring a rigid bicyclic pinane-type framework. This compound is valued for its role as a sophisticated building block in advanced pharmaceutical synthesis and fine chemical research, where its unique steric and electronic properties are leveraged. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the development of advanced, stereospecific pesticides and herbicides.
• Chiral Catalyst & Ligand Development: Serves as a scaffold for creating novel asymmetric catalysts used in enantioselective synthesis.
• Peptidomimetics & Bioactive Molecule Design: The constrained bicyclic structure is incorporated to mimic peptide turns and enhance metabolic stability.
• Fine Chemical & Flavor/Fragrance Intermediate: Employed in the synthesis of complex, high-value odorants and flavor compounds.
• Academic & Industrial Research: A valuable tool for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Item	Detail
Product Name	Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl-
CAS No.	705948-99-8
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	2-Amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid; 2-Amino-2,6,6-trimethyl-3-norpinane-3-carboxylic acid; 3-Carboxy-2,6,6-trimethyl-2-aminonorpinane; (1R,2R,5R)-2-Amino-2,6,6-trimethylbicyclo[3.1.1]heptane-3-carboxylic acid (for specific enantiomer); Pinane-based amino acid; Trimethylnorpinane amino acid derivative
EINECS	Contact for details

Quality Control

Every batch of our Bicyclo[3.1.1]Heptane-3-Carboxylic Acid, 2-Amino-2,6,6-Trimethyl- is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including chiral purity assessment, is performed. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e. (for specified enantiomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.