Description

3-(4-Carbamoyl-Piperazin-1-Yl)-Propionic Acid is a high-purity, functionalized piperazine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional nature, featuring both a reactive carboxylic acid group and a carbamoyl-substituted piperazine ring, enabling its use in constructing complex molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and GPCR-targeted therapeutic programs.
• Linker Molecule in Bioconjugation: Used to create peptide-drug conjugates or antibody-drug conjugates (ADCs) due to its carboxylic acid handle for amide bond formation.
• Agrochemical Research: Serves as a precursor in the synthesis of new-generation herbicides and fungicides with enhanced activity profiles.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysis in asymmetric synthesis.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce polar, hydrogen-bonding groups into polymer backbones.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	3-(4-Carbamoyl-Piperazin-1-Yl)-Propionic Acid
CAS No.	705941-74-8
Molecular Formula	C8H15N3O3
Molecular Weight	201.22 g/mol
Synonyms	3-(4-Carbamoylpiperazin-1-yl)propanoic Acid; 1-(2-Carboxyethyl)-4-carbamoylpiperazine; 4-Carbamoyl-1-(2-carboxyethyl)piperazine; 3-(4-Carbamoyl-1-piperazinyl)propionic Acid; Piperazine-1-carboxamide, 4-(2-carboxyethyl)-; 705941-74-8; 3-(4-Carbamoylpiperazin-1-yl)propionic Acid
EINECS	Contact for details

Quality Control

Our 3-(4-Carbamoyl-Piperazin-1-Yl)-Propionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.