Description

4-(4-Piperazin-1-Yl-Benzenesulfonyl)-Morpholine is a high-purity sulfonamide-based organic building block of significant interest in advanced chemical synthesis. This compound matters as a critical intermediate for developing novel pharmaceutical candidates, particularly in therapeutic areas requiring complex molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to create novel drug candidates with improved efficacy and selectivity.
• Chemical Biology Probes: Serves as a core structure for synthesizing molecular probes to study biological pathways and protein functions.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial manufacturing.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	4-(4-Piperazin-1-Yl-Benzenesulfonyl)-Morpholine
CAS No.	704873-20-1
Molecular Formula	C14H21N3O3S
Molecular Weight	311.40 g/mol
Synonyms	4-(4-Piperazin-1-ylbenzenesulfonyl)morpholine; 4-Morpholino-4-(piperazin-1-ylsulfonyl)diphenyl sulfone; 4-(Piperazin-1-yl)-N-(morpholin-4-ylsulfonyl)benzenesulfonamide; 704873-20-1; Benzenesulfonamide, 4-(1-piperazinyl)-N-4-morpholinylsulfonyl-; 4-(1-Piperazinyl)-N-(4-morpholinylsulfonyl)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our 4-(4-Piperazin-1-Yl-Benzenesulfonyl)-Morpholine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.