Description

1-Palmitoyl-2-Oleoylphospatidylserine is a high-purity, synthetic phosphatidylserine (PS) species, a critical phospholipid component of cell membranes. Its defined fatty acid composition at the sn-1 and sn-2 positions provides superior consistency and performance for advanced research and formulation development. This product is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced biomaterials sectors requiring a specific, well-characterized phospholipid for liposomal drug delivery systems, membrane biophysics studies, and cognitive health applications.

Application

• Liposomal Drug Delivery: A key excipient for formulating stable, targeted liposomes and lipid nanoparticles (LNPs) for encapsulating therapeutic agents.
• Biomedical Research: Used in membrane biology studies, cell signaling research, and as a standard for analytical method development.
• Nutraceutical Formulations: Incorporated into high-end dietary supplements targeting cognitive support and brain health.
• Biomimetic Membranes: Serves as a building block for creating artificial cell membranes and sensor coatings.
• Cosmetic Actives: Employed in advanced skincare formulations for its purported cell-communicating and skin barrier repair properties.
• Diagnostic Reagents: Used in the development of diagnostic assays and kits that involve membrane interactions.

Basic Information

Product Name	1-Palmitoyl-2-Oleoylphospatidylserine
CAS No.	79980-16-8
Molecular Formula	C39H74NO10P
Molecular Weight	739.99 g/mol
Synonyms	POPS; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phospho-L-serine; (3-sn-Phosphatidyl)-L-serine, 1-palmitoyl-2-oleoyl-; PS(16:0/18:1); Phosphatidylserine (16:0/18:1); L-α-Phosphatidylserine (palmitoyl-oleoyl); 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoserine
EINECS	279-356-0

Quality Control

Our 1-Palmitoyl-2-Oleoylphospatidylserine is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Once opened, use promptly and reseal under inert gas. The material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (sn-1 / sn-2)	≥ 95% Palmitic / Oleic acid
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.