Description

1,2-4,4-Difluoromyristoyl-Sn-Glycero-3-Phosphorylcholine is a synthetic, fluorinated phospholipid analog, a key building block in advanced material science and biomedical research. Its unique structure, featuring fluorinated acyl chains, is engineered to enhance membrane stability and modulate biophysical properties in lipid assemblies. This high-purity specialty chemical is essential for researchers and formulators in liposome development, drug delivery systems, and membrane biophysics studies, where precise control over lipid composition is critical.

Application

• Liposome Formulation: As a component to create fluorinated or stable liposomes for targeted drug delivery and vaccine adjuvants.
• Membrane Protein Research: Used in the reconstitution and stabilization of membrane proteins for structural and functional analysis.
• Biomimetic Membranes: Serves as a key lipid for constructing model membranes with tailored fluidity and permeability characteristics.
• Diagnostic Agents: Potential use in the development of contrast agents for medical imaging techniques like 19F MRI.
• Surface Coatings: Utilized in creating biocompatible and low-fouling surface coatings for medical devices.
• High-Value Chemical Synthesis: Acts as a sophisticated intermediate for the synthesis of more complex fluorinated phospholipids and prodrugs.

Basic Information

Product Name	1,2-4,4-Difluoromyristoyl-Sn-Glycero-3-Phosphorylcholine
CAS No.	79962-98-4
Molecular Formula	C36H71F2NO8P
Molecular Weight	706.92 g/mol
Synonyms	DFMPC; 1,2-Di(4,4-difluorotetradecanoyl)-sn-glycero-3-phosphocholine; 1,2-Bis(4,4-difluoromyristoyl)-sn-glycero-3-phosphocholine; Fluorinated DMPC analog; 1,2-Difluoromyristoyl Phosphatidylcholine; Phosphatidylcholine, 1,2-di(4,4-difluorotetradecanoyl)-sn-glycero-3-; Fluorolipid 14:0(4,4-F2)
EINECS	Contact for details

Quality Control

Every batch of our fluorinated phospholipids is produced and analyzed under strict quality protocols to ensure high purity and batch-to-batch consistency, critical for reproducible research and development outcomes. Our standard research-grade material is characterized by multiple analytical techniques including NMR and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., argon or nitrogen) in a cool, dry place. For long-term stability, storage at -20°C or below is recommended. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.