Description

Trequinsin CAS NO 79855-88-2 is a high-purity, small-molecule compound belonging to the class of selective phosphodiesterase (PDE) inhibitors. This compound is of significant value in pharmaceutical research and development due to its specific biological activity. It is primarily required by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in cardiovascular and metabolic disease research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting PDE inhibition.
• Biochemical Research: Used as a selective tool compound in in vitro and ex vivo studies to investigate PDE enzyme function and signaling pathways.
• Preclinical Development: Employed in animal model studies for evaluating the efficacy and pharmacokinetics of novel therapeutic candidates for hypertension and related conditions.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation of related pharmaceutical products.
• Life Science Reagent: Supplied to academic and industrial laboratories for fundamental research in cell biology and pharmacology.

Basic Information

Product Name	Trequinsin
CAS No.	79855-88-2
Molecular Formula	C20H21N3O3
Molecular Weight	351.40 g/mol
Synonyms	HL 725; 1,3-Dimethyl-6-(2-propoxybenzylamino)-2,4(1H,3H)-pyrimidinedione; 6-[(2-Propoxyphenyl)methylamino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione; 6-[(2-Propoxyphenyl)methylamino]-1,3-dimethyluracil; Trequinsine
EINECS	Contact for details

Quality Control

Our Trequinsin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results against predefined specifications is provided with every shipment to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.