Description

Leukotriene E5 is a specialized eicosanoid metabolite derived from the lipoxygenase pathway, playing a significant role in inflammatory and immune response signaling. This compound is crucial for advanced biochemical research and pharmaceutical development targeting specific leukotriene receptors. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of asthma, allergic responses, and other inflammatory disease mechanisms. Leukotriene E5 CAS NO 79695-14-0 represents a high-purity reference standard for precise analytical and experimental work.

Application

• Biochemical Research: Used as a critical reference standard in studies investigating the 5-lipoxygenase pathway and eicosanoid biosynthesis.
• Pharmaceutical R&D: Serves as a key intermediate or target molecule in the development of novel anti-inflammatory and anti-asthma therapeutics.
• Cell Signaling Studies: Applied in in vitro and in vivo models to elucidate the role of cysteinyl leukotrienes in immune system regulation.
• Analytical Method Development: Employed as a high-purity calibrant for developing and validating LC-MS/MS, HPLC, and other chromatographic assays in bioanalytical laboratories.
• Metabolomics: Acts as a defined metabolite in profiling studies to understand disease states related to inflammation and oxidative stress.

Basic Information

Product Name	Leukotriene E5
CAS No.	79695-14-0
Molecular Formula	C23H37NO5S
Molecular Weight	439.61 g/mol
Synonyms	LTE5; (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoic acid; 5(S),6(R)-LTE5; 6-Cysteinyl-5-hydroxy-7E,9E,11Z,14Z-eicosatetraenoic acid; Leukotriene E5; Cysteinylleukotriene E5
EINECS	Contact for details

Quality Control

Our Leukotriene E5 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization using techniques including HPLC, MS, and NMR to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to relevant industry standards suitable for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, solutions should be prepared in appropriate solvents and kept at -80°C. The product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in ethanol, DMSO; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.