Description

(3R,6S)-3,6-Bis(Hydroxymethyl)-2,5-Piperazinedione is a high-purity chiral piperazinedione derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the production of complex pharmaceuticals and bioactive molecules, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other complex drug candidates.
• Peptidomimetics Research: Serves as a constrained scaffold or building block in the design and development of novel peptidomimetic compounds.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to introduce chirality.
• Agrochemical Development: Used in the research and production of advanced, stereospecific pesticides and herbicides.
• Ligand and Catalyst Preparation: Acts as a precursor for chiral ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(3R,6S)-3,6-Bis(Hydroxymethyl)-2,5-Piperazinedione
CAS No.	79617-26-8
Molecular Formula	C6H10N2O4
Molecular Weight	174.16 g/mol
Synonyms	(3R,6S)-3,6-Di(hydroxymethyl)piperazine-2,5-dione; (3R,6S)-3,6-Bis(hydroxymethyl)-2,5-diketopiperazine; (3R,6S)-3,6-Di(hydroxymethyl)-2,5-diketopiperazine; (3R,6S)-3,6-Bis(hydroxymethyl)piperazine-2,5-dione; (3R,6S)-Bis(hydroxymethyl)DKP; (3R,6S)-Bis-HMDKP; Chiral Bis-HMDKP; (3R,6S)-HMDKP
EINECS	Contact for details

Quality Control

Our (3R,6S)-3,6-Bis(Hydroxymethyl)-2,5-Piperazinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.