Description

11,14,15-Trihydroxyeicosa-5,8,12-Trienoic Acid is a specialized polyhydroxy fatty acid derivative of significant interest in biochemical research and development. This compound serves as a key intermediate and reference standard for studying eicosanoid pathways, lipid metabolism, and related biological signaling mechanisms. It is primarily utilized by research institutions and pharmaceutical developers focused on inflammation, cardiovascular, and metabolic disorders.

Application

• Biochemical Research: Used as a high-purity reference standard and intermediate in the study of lipoxygenase and cytochrome P450 metabolic pathways.
• Pharmaceutical R&D: Serves as a critical building block for the synthesis of novel eicosanoid analogs and potential therapeutic agents.
• Cell Signaling Studies: Applied in in vitro assays to investigate the role of specific hydroxyeicosatrienoic acids (HETEs) in cellular processes.
• Analytical Chemistry: Employed as a certified standard for method development and validation in chromatographic analysis (HPLC, LC-MS).
• Academic Research: Utilized in universities and research institutes for fundamental studies in lipidomics and inflammation biology.

Basic Information

Product Name	11,14,15-Trihydroxyeicosa-5,8,12-Trienoic Acid
CAS No.	79595-81-6
Molecular Formula	C₂₀H₃₄O₅
Molecular Weight	354.48 g/mol
Synonyms	11,14,15-TriHETE; 11,14,15-Trihydroxy-5,8,12-eicosatrienoic acid; 11(R),14(S),15(S)-Trihydroxy-5(Z),8(Z),12(E)-eicosatrienoic acid; 11,14,15-Trihydroxyicosatrienoic acid; (±)11,14,15-TriHETE; 11,14,15-THETA; 5,8,12-Eicosatrienoic acid, 11,14,15-trihydroxy-; (±)-11,14,15-Trihydroxy-5Z,8Z,12E-eicosatrienoic acid
EINECS	Contact for details

Quality Control

Our 11,14,15-Trihydroxyeicosa-5,8,12-Trienoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to ISO 9001 standards, and our analytical methods are validated to meet the rigorous demands of pharmaceutical and academic research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the material desiccated to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.