Description

1H-Pyrazole-4-Carbonyl Chloride, 1-Methyl- (9Ci) is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing pyrazole-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) containing the 1-methylpyrazole moiety.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage pyrazole chemistry.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific thermal or electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: Facilitates exploratory chemistry in university and corporate laboratories for drug discovery and new compound libraries.

Basic Information

Product Name	1H-Pyrazole-4-Carbonyl Chloride, 1-Methyl- (9Ci)
CAS No.	79583-19-0
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	1-Methyl-1H-pyrazole-4-carbonyl chloride; 1-Methylpyrazole-4-carbonyl chloride; 1-Methyl-4-pyrazolecarbonyl chloride; 4-Carboxy-1-methylpyrazole chloride; 1-Methyl-1H-pyrazole-4-carboxylic acid chloride; 79583-19-0; 1-Methylpyrazole-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-4-Carbonyl Chloride, 1-Methyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.