Description

20-Carboxyarachidonic Acid is a specialized, high-purity eicosanoid derivative, a key metabolite in the arachidonic acid cascade. This compound is crucial for advanced biochemical research and the development of analytical standards. It serves as an essential intermediate and reference material for researchers and manufacturers in the pharmaceutical and life science sectors, particularly those investigating inflammation, lipidomics, and metabolic pathways.

Application

• Biochemical Research: Critical intermediate for studying eicosanoid metabolism, inflammation pathways, and signal transduction mechanisms.
• Pharmaceutical Development: Used as a reference standard and a potential synthetic precursor in drug discovery programs targeting lipid-mediated diseases.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quantitative analysis via LC-MS, HPLC, and GC-MS in metabolomics and lipidomics.
• Enzyme Substrate/Inhibitor Studies: Employed in in vitro assays to investigate the activity of cytochrome P450 enzymes, lipoxygenases, and other oxidoreductases.
• Cell Signaling Research: A vital tool for probing the role of oxylipins in cellular communication, immune response, and oxidative stress.

Basic Information

Product Name	20-Carboxyarachidonic Acid
CAS No.	79551-84-1
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	20-COOH-AA; 20-Carboxy-5Z,8Z,11Z,14Z-eicosatetraenoic Acid; 20-COOH-Arachidonic Acid; 20-Carboxy-AA; 20-Carboxyarachidonate; 20-Oxo-AA Metabolite; ω-Carboxyarachidonic Acid; 20-COOH-5,8,11,14-Eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our 20-Carboxyarachidonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and stability. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with our stringent specifications for research and analytical use.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.