Description

(1As,4E)-1Aα,3,6,6Aβ,7,9Aβ,10,10A-Octahydro-6β-Hydroxy-4,10Aβ-Dimethyl-7-Methyleneoxireno[8,9]Cyclodeca[1,2-B]Furan-8(2H)-One is a high-purity, complex sesquiterpene lactone derivative with a unique oxireno-fused cyclodecane structure. This compound is valued for its sophisticated molecular architecture, which serves as a critical advanced intermediate or reference standard in specialized organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of complex natural product analogs and potential therapeutic agents.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related sesquiterpene compounds.
• Organic Synthesis Research: Employed in academic and industrial research to study novel cycloaddition reactions and ring transformations due to its strained oxireno and furanone moieties.
• Agrochemical Development: Investigated as a precursor for novel bioactive molecules with potential insecticidal or herbicidal activity.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty fragrances, flavors, or other high-value chemicals requiring specific stereochemistry.

Basic Information

Product Name	(1As,4E)-1Aα,3,6,6Aβ,7,9Aβ,10,10A-Octahydro-6β-Hydroxy-4,10Aβ-Dimethyl-7-Methyleneoxireno[8,9]Cyclodeca[1,2-B]Furan-8(2H)-One
CAS No.	79495-95-7
Molecular Formula	C15H18O4
Molecular Weight	262.30 g/mol
Synonyms	6β-Hydroxy-4,10aβ-dimethyl-7-methylidene-1a,3,4,6,6a,7,9a,10,10a,10b-decahydrooxireno[8,9]cyclodeca[1,2-b]furan-8-one; Parthenolide analog; Parthenolide derivative; Oxireno[8,9]cyclodeca[1,2-b]furan-8-one derivative; Sesquiterpene lactone intermediate; (1aS,4E,6R,6aR,9aR,10aR,10bS)-6-Hydroxy-4,10a-dimethyl-7-methylidene-dodecahydrooxireno[8,9]cyclodeca[1,2-b]furan-8-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized using modern analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with each shipment, supporting its use in cGMP-compliant research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to heat and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.