Description

3-Methyl-2-Butenoic Acid [(3Ar)-2,3,3A,4,5,7,7Aα,8A,8B,8Cα-Decahydro-8Bβ-Hydroxy-6,8Aα-Dimethyl-3-Methylene-2,7-Dioxooxireno[2,3]Azuleno[4,5-B]Furan-4α-Yl] Ester is a high-purity, complex organic ester derivative with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate and a valuable scaffold in synthetic organic chemistry. Its intricate fused-ring structure makes it an essential building block for the research and development of novel active pharmaceutical ingredients (APIs), particularly in specialized therapeutic areas. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex molecules for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of proprietary drug candidates and complex natural product analogs.
• Medicinal Chemistry Research: Used as a sophisticated molecular scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions for API production.
• Organic Synthesis Reagent: Employed in advanced synthetic methodologies, including stereoselective reactions and the construction of complex polycyclic frameworks.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	3-Methyl-2-Butenoic Acid [(3Ar)-2,3,3A,4,5,7,7Aα,8A,8B,8Cα-Decahydro-8Bβ-Hydroxy-6,8Aα-Dimethyl-3-Methylene-2,7-Dioxooxireno[2,3]Azuleno[4,5-B]Furan-4α-Yl] Ester
CAS No.	79421-63-9
Molecular Formula	C₂₀H₂₄O₇
Molecular Weight	376.40 g/mol
Synonyms	3-Methylbut-2-enoic acid (3aR,4S,7aS,8aR,8bS,8cS)-decahydro-8b-hydroxy-6,8a-dimethyl-3-methylene-2,7-dioxooxireno[2,3]azuleno[4,5-b]furan-4-yl ester; Artemisolide; Arteannuin B peroxy lactone derivative; 3-Methylcrotonic acid arteannuin B peroxy lactone ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Identity and purity are confirmed through a suite of analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support development and commercial projects with material suitable for research use or produced under GMP-like controls for non-clinical applications, as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to heat and moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.