Description

4-(4-Hydroxy-Piperidin-1-Yl)-Benzonitrile is a versatile and high-value pharmaceutical intermediate and fine chemical building block. Its molecular structure, featuring both a piperidine ring and a benzonitrile group, makes it a critical precursor in modern organic synthesis, particularly for the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and advanced material sectors seeking to develop novel compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its structural motifs for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science: Acts as a monomer or cross-linking agent in the research of advanced polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-(4-Hydroxy-Piperidin-1-Yl)-Benzonitrile
CAS No.	79421-43-5
Molecular Formula	C₁₂H₁₄N₂O
Molecular Weight	202.25 g/mol
Synonyms	1-(4-Cyanophenyl)-4-piperidinol; 4-(4-Hydroxy-1-piperidinyl)benzonitrile; 4-Cyano-N-(4-hydroxypiperidin-1-yl)benzene; 4-Piperidinol, 1-(4-cyanophenyl)-; 79421-43-5; 4-(4-Hydroxypiperidino)benzonitrile; 4-(4-Hydroxy-1-piperidyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-(4-Hydroxy-Piperidin-1-Yl)-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.