Description

D-α-(4-Ethyl-2,3-Dioxo-1-Piperazinecarboxamido)-β-(S)-tert-Butoxybutyric Acid is a sophisticated chiral building block and protected amino acid derivative of significant importance in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex peptide-based pharmaceuticals and fine chemicals, offering precise stereochemical control. This high-purity compound is essential for research and development chemists and process engineers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for API development.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel peptide-based Active Pharmaceutical Ingredients (APIs) and therapeutic agents.
• Peptidomimetics Research: Used in the design and synthesis of peptidomimetics, which are molecules that mimic the structure and function of peptides but with enhanced stability and bioavailability.
• Protected Amino Acid Derivative: Serves as a protected form of an amino acid, allowing for selective chemical reactions during complex peptide chain assembly without interference from other functional groups.
• Asymmetric Synthesis: Employed in asymmetric synthesis protocols to introduce specific stereocenters into target molecules, crucial for developing drugs with high enantiomeric purity.
• Process Chemistry & Scale-up: Used in process research and development for optimizing synthetic routes from laboratory to pilot and commercial scale production.
• Bioconjugation & Probe Development: Potential utility in creating labeled peptides or bioconjugates for diagnostic and research applications.

Basic Information

Product Name	D-α-(4-Ethyl-2,3-Dioxo-1-Piperazinecarboxamido)-β-(S)-tert-Butoxybutyric Acid
CAS No.	79276-23-6
Molecular Formula	C15H25N3O6
Molecular Weight	343.38 g/mol
Synonyms	D-α-[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino-β-(S)-tert-butoxybutyric Acid; (2S)-2-[[(2R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)formamido]-4-(tert-butoxy)butanoyl]amino]acetic Acid (related form); Nα-(4-Ethyl-2,3-dioxo-1-piperazinecarbonyl)-D-α-amino-β-(S)-tert-butoxybutyric Acid; Protected D-α-Amino-β-(S)-tert-Butoxybutyric Acid Piperazine Derivative; 79276-23-6; D-α-(4-Ethyl-2,3-dioxo-1-piperazinecarboxamido)-β-(S)-tert-butoxybutanoic Acid
EINECS	Contact for details

Quality Control

Our D-α-(4-Ethyl-2,3-Dioxo-1-Piperazinecarboxamido)-β-(S)-tert-Butoxybutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.