Description

1,3-Dioxolane-4-Carboxaldehyde, 2,2,4-Trimethyl-, (4S)- (9Ci) is a specialized chiral aldehyde derivative of 1,3-dioxolane, serving as a high-value synthetic building block. This compound matters for its role in asymmetric synthesis, where its defined stereochemistry at the 4-position enables the construction of complex molecules with precise spatial orientation. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands used in transition metal catalysis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical fidelity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, exploring new carbon-carbon bond forming reactions.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2,2,4-Trimethyl-, (4S)- (9Ci)
CAS No.	79243-92-8
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(4S)-2,2,4-Trimethyl-1,3-dioxolane-4-carboxaldehyde; (S)-2,2,4-Trimethyl-1,3-dioxolane-4-carbaldehyde; L-Glyceraldehyde Acetonide; (S)-Glyceraldehyde Acetonide; (S)-1,2-O-Isopropylidene-glyceraldehyde; (4S)-2,2,4-Trimethyl-1,3-dioxolane-4-carboxaldehyde (9CI); 1,3-Dioxolane-4-carboxaldehyde, 2,2,4-trimethyl-, (4S)-
EINECS	Contact for details

Quality Control

Our production of 1,3-Dioxolane-4-Carboxaldehyde, 2,2,4-Trimethyl-, (4S)- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Due to its highly volatile and easily oxidized nature, prolonged exposure to air, heat, or light should be avoided. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.