Description

(2S,4S)-4-Methyl Pipecolic Acid CAS NO 79199-63-6 is a high-purity, non-proteinogenic amino acid derivative characterized by its specific stereochemistry at the 2 and 4 positions. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is essential for research and production in medicinal chemistry, peptide mimetics, and the synthesis of complex natural products, where precise stereochemical control is paramount for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, receptor antagonists, and other active pharmaceutical ingredients (APIs).
• Peptidomimetics & Drug Discovery: Used to construct constrained peptide analogs and scaffolds in medicinal chemistry programs to enhance metabolic stability and binding affinity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective catalytic reactions to introduce complex molecular architectures.
• Biochemical Research: Utilized as a standard or reagent in studies of enzyme mechanisms, metabolic pathways, and neurotransmitter analogs.
• Agrochemical Development: Acts as a precursor for novel chiral compounds with potential herbicidal or insecticidal activity.

Basic Information

Product Name	(2S,4S)-4-Methyl Pipecolic Acid
CAS No.	79199-63-6
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(2S,4S)-4-Methylpipecolic Acid; (2S,4S)-4-Methyl-2-piperidinecarboxylic Acid; (2S,4S)-HMPA; (2S,cis)-4-Methylpipecolic Acid; 4-Methyl-DL-pipecolic Acid (stereoisomer); 4-Methylpipecolic Acid; L-4-Methylpipecolic Acid; 79199-63-6
EINECS	Contact for details

Quality Control

Our (2S,4S)-4-Methyl Pipecolic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.