Description

(2R-Cis)-4-Methyl-2-Piperidinecarboxylic Acid Ethyl Ester is a high-purity chiral piperidine derivative, a crucial building block in advanced organic synthesis. Its defined stereochemistry and functional group versatility make it an essential intermediate for creating complex molecules with specific biological activity. This compound is primarily sought by pharmaceutical and agrochemical research organizations for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potent drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used as a precursor for developing novel pesticides and herbicides with enhanced efficacy and selectivity.
• Asymmetric Catalysis: Serves as a chiral ligand precursor or auxiliary in catalytic processes to induce stereoselectivity.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialty chemicals and complex organic molecules.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(2R-Cis)-4-Methyl-2-Piperidinecarboxylic Acid Ethyl Ester
CAS No.	79199-61-4
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl (2R,4R)-4-Methylpipecolate; Ethyl (2R,4R)-4-Methylpipecolinate; L-trans-4-Methylpipecolic Acid Ethyl Ester; (2R,4R)-4-Methyl-2-piperidinecarboxylic Acid Ethyl Ester; Ethyl cis-4-Methyl-D-pipecolate; (2R-cis)-4-Methyl-2-piperidinecarboxylic acid, ethyl ester; Ethyl 4-methyl-2-piperidinecarboxylate (cis, R,R- isomer)
EINECS	Contact for details

Quality Control

Our (2R-Cis)-4-Methyl-2-Piperidinecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.