Description

2-(Bromomethyl)-3,5,6-Trimethylpyrazine is a versatile brominated pyrazine derivative, a key building block in advanced organic synthesis. Its reactive bromomethyl group makes it a critical intermediate for constructing complex molecules, offering high selectivity and efficiency in cross-coupling and alkylation reactions. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and flavor & fragrance industries seeking to introduce functionalized pyrazine moieties.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted pyrazine rings.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyrazine core contributes to biological activity.
• Flavor & Fragrance Chemistry: Acts as a key intermediate for creating complex aroma compounds, as alkylpyrazines are significant contributors to roasted, nutty, and earthy notes.
• Material Science Research: Employed in the synthesis of organic ligands for catalysts or as a monomer for constructing specialized polymers and functional materials.
• Chemical Biology & Proteomics: Utilized as a reactive handle for bioconjugation, enabling the labeling or modification of biomolecules for research and diagnostic applications.

Basic Information

Product Name	2-(Bromomethyl)-3,5,6-Trimethylpyrazine
CAS No.	79074-45-6
Molecular Formula	C8H11BrN2
Molecular Weight	215.09 g/mol
Synonyms	3,5,6-Trimethyl-2-(bromomethyl)pyrazine; 2-(Bromomethyl)-3,5,6-trimethyl-1,4-diazine; Pyrazine, 2-(bromomethyl)-3,5,6-trimethyl-; 3,5,6-Trimethylpyrazine-2-methyl bromide
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-3,5,6-Trimethylpyrazine is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards through rigorous analytical controls, including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere if necessary to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.